Omnicom Health Medical Communications

SXSW 2026:Decodedfor Med Comms

A Med Comms Lens on the Signals That Matter

The way people communicate, connect, and consume information are constantly being rewritten. The platforms they use, the content they trust, the experiences they expect—all of it is in flux.

The best medical communicators don’t wait for trends to arrive in healthcare—they anticipate them. That’s why we brought together a handpicked, multidisciplinary team spanning commercial, medical affairs, and creative to attend SXSW 2026—to experience innovation firsthand and uncover what’s next for our industry.

This report highlights five key signals observed at SXSW and their implications for Med Comms, alongside a visual photo wall capturing moments from the conference and a snapshot of how Pharma showed up across the programme, partnerships, and activations.

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Five signals from SXSW 2026

Click on a signal to reveal or hide the detail

The Signal

We’re building a world that’s faster and smoother—while people quietly crave what’s slower, physical, and real. At SXSW, one theme kept resurfacing: it’s getting harder to capture and keep attention, and AI’s promise of fewer steps and more output only speeds that up. But when you remove friction everywhere, things start to feel weightless. That’s why an analog counterculture is emerging: not against AI, just a desire to feel things again. Think “Grandma hobbies,” vinyl, and even Blackwing pencils—small resistance that slows you down enough to think. As everything gets effortless, intention becomes the premium layer.

Implications for Med Comms

Focus on clearer narratives and fewer, stronger claims to avoid losing attention.

For many HCPs, in-person peer-to-peer (P2P) events are the analog counterpoint to AI—enabling slower, more intentional scientific exchange where judgment, nuance, and lived clinical experience matter most.

A simple strategy that can be applied across all P2P, whether in person or virtual, is to deliberately reintroduce moments of friction and human connection into the agenda: incorporate reflective questions, protect time for discussion and build in moments for individual and collective reflection. Consider setting up journal clubs or case discussion groups as ways to maintain connection and reflection between events.

The Signal

Storytelling is fundamental to being human, yet several sessions at SXSW 2026 questioned what role—if any—human storytellers will play in the brave new world of generative AI. A standout session came from Omnicom’s Sarah DaVanzo (Global Chief Innovation Officer, Porter Novelli), who shared insights from her forthcoming book EXOTIC Thinking: A Curious Edge in the Age of AI.

DaVanzo argues that as AI excels at pattern-matching and consensus-driven knowledge, human value lies in thinking where machines cannot. Her work explores six such under-documented and hard-to-codify territories—Esoteric, X-mapped, Outsider, Transgressive, Inception and Curious—framed as both an acronym and a mindset. Her work goes on to demonstrate how exploring these spaces using tried-and-tested provocations and challenges can provide a framework generating ideas that are more original and emotionally resonant than any machine-averaged AI outputs.

Implications for Med Comms

AI can generate language at scale, but it cannot generate originality, emotional intelligence, or cultural nuance. Brands that over-rely on AI risk becoming part of the ‘sea of sameness’. Human storytellers, whose ability to find unique angles, uncover the emotional center, and make non-obvious connections, remain vital to creating stories that feel fresh, original, and differentiating. Storytelling, at least for now, should remain a human-led process where AI supports efficiency, but humans shape interpretation, tone, and scientific meaning.

The Signal

This year’s SXSW marked a clear departure from immersive tech as spectacle. Traditional demos and novelty activations were largely absent, replaced by AR and VR experiences that sat quietly in service of storytelling—amplifying narrative, context, and emotional understanding rather than drawing attention to the technology itself. Two experiences stood out:

Spectacular: The Art of Jonathan Yeo

A Jonathan Yeo portrait exhibition transformed a typically passive viewing experience into one of active participation. Visitors entering the exhibition wore Snap Spectacles (AR glasses) and as they approached the portraits, the works seemingly came to life with both movement and sound. The interactive experiences were activated using object recognition and proximity triggers, but from the user perspective, the interaction unfolded naturally without interruption or instruction, marking a shift from demanded attention to ambient engagement, where the experience enhances meaning without persuasion.

Immersive Expeditions – Excurio

VR specialist Excurio showcased Immersive Expeditions, a platform designed for shared learning at scale. Moments of cultural or scientific importance are meticulously recreated in VR and mapped onto large physical spaces, allowing up to 100 participants to move through the experience simultaneously. Unlike isolated headset use, the experience felt collective, spatial, and orchestrated for group exploration.

Implications for Med Comms

Across immersive storytelling, the clear shift is toward ambient and shared experience, where people nearby can at least intuitively understand what is happening without explanation.

For pharma, this points to congress environments where booths themselves carry the scientific or disease narrative, supported by subtle AR layers that are visible, discussable, and intelligible to others—reinforcing shared learning and scientific exchange. For now, VR remains best deployed as a black-box experience for selective moments that benefit from isolation and depth, such as empathy building, skills training, or deep mechanistic understanding.

The Signal

At SXSW 2026, it became clear that immersive storytelling is entering a multisensory era—one where stories are designed to be felt, not just consumed. The most compelling experiences moved beyond visual spectacle to engage emotion, memory, and the body itself.

An olfactory breakthrough

Smell emerged as a powerful—and underexplored—frontier. Unlike sight or sound, olfaction has a direct pathway to the brain’s limbic system, making it uniquely effective at triggering emotion, memory, and association. A single scent can instantly evoke a place, mood, or lived experience, giving it disproportionate impact on recall and emotional connection.

Until recently, creating a signature scent was complex and expensive. OSMO is changing this by digitizing smell. Using AI to map and design scent, OSMO has made it easy for anyone to create a custom fragrance from simple descriptors like emotions, images, or music. Beyond branding, their work points toward future health applications—from disease detection via scent biomarkers to sensory-led wellbeing and memory care.

The implications are striking; think about what “bottling nostalgia” could mean for dementia patients. Or picture a busy congress floor where a subtle, welcoming scent at a booth differentiates a brand and makes it more memorable—without adding another screen.

Multisensory and Embodied Storytelling

At SXSW, the strongest work treated sound, touch, scent, and physiology as core narrative components—not embellishments. Deepa MannKler’s The Baby Factory Is Now Closed was one of the most vivid examples. Her 20-minute VR experience reframes menopause by placing audiences inside the body of a British-born Sikh woman named Zoraan who is navigating menopause amid climate crisis, surveillance culture and medical bias. Through haptics, scent, and biometric feedback, the audience feels tension, disorientation, vulnerability, and release rather than simply hearing about them. Abstract concepts become visceral, embodied experiences—designed to be physically felt rather than passively observed.

Implications for Med Comms

SXSW 2026 this signals a shift from information delivery toward experience design. Multisensory approaches offer new ways to communicate symptoms, disease burden, and treatment impact that are difficult to convey through words or visuals alone. For Med Comms, the opportunity lies in using sensory and embodied elements deliberately—to enhance understanding and empathy—while maintaining accessibility and scientific integrity.

Crucially, the impact on memory makes this effort worthwhile. Data from our colleagues in experiential marketing (GMR) shows that consumers are six times more likely to remember a brand when it matters most when the experience is multisensory, highly engaging, and contextually relevant. In a crowded congress or digital environment where attention is scarce and recall matters, well-executed multisensory experiences can significantly strengthen message retention.

The Signal

At SXSW 2026, play was reframed as a serious tool for learning and creativity—not a distraction. In Innovators Today and the Future of Play, speakers highlighted that 94% of people believe play is for all ages, and around 70% say their most creative thinking happens through play.

In healthcare education, this signals a shift away from superficial “gamification” toward designed practice. The goal is not just to make learning fun, but to create purposeful, low-friction experiences where HCPs can test decisions, make mistakes safely, receive immediate feedback, and improve judgment, confidence, and speed.

The most effective examples started with the decision that needs improving, then worked backwards. A simple framework shared at SXSW—Goal → Motivation → Mechanics → Tension—keeps learning intent ahead of tactics. When mechanics serve the educational goal (rather than the other way around), challenge becomes meaningful rather than gimmicky.

Done well, game-based learning aligns naturally with adult learning principles, supporting learning through action, feedback, reflection, and adjustment—mirroring how clinical expertise is built in the real world.

Implications for Med Comms

For Med Comms, responsible gamification starts with respecting context: HCPs are time-poor, outcomes matter, and credibility is critical. The opportunity lies in designing learning experiences that challenge clinical intuition, surface gaps between evidence and instinct, and allow recalibration through safe, consequence-driven exploration.

Used thoughtfully, gamification becomes a learning architecture—not just because it entertains, but because it also demands active thinking, reinforces clinical reasoning, and makes evidence more usable in practice.

Industry Watch

How Did Pharma Show Up?

Pharma was noticeably less present than previous years, nonetheless, three companies stood out.

Redefining Healthcare

Eli Lilly

As a major sponsor, Eli Lilly was the most visible pharma company at SXSW, organizing multiple panel discussions, a fireside chat, and an immersive activation at the innovation clubhouse.

Their program was notably strategic. They paired science-led conversations on drug discovery and early Alzheimer’s diagnosis with everyday wellness topics—stress, sleep, food, movement, and connection—effectively framing medicine as integrated into daily life, not isolated from it.

Their immersive activation, “Putting Health Above All,” offered congress attendees a space to recharge through simple, non-medical health guidance and restorative experiences.

By moving upstream from disease management to holistic wellness, Lilly sets itself apart from other Pharma and signals a modern vision of healthcare.

Explore Eli Lilly’s Well-Being Library
Cultural Reach

Gilead

Gilead convened experts from music, marketing, and media to explore how pop culture can expand the reach of HIV prevention.

While 2.2 million Americans could benefit from Pre-Exposure Prophylaxis (PrEP), only around 500,000 currently use it. Recognizing that traditional healthcare messaging wasn’t reaching these audiences, Gilead looked beyond health for a new approach. Partnering with pop singer Ciara, they lyrically reimagined her hit song “1, 2 Step” to raise awareness of a novel PrEP option and normalize conversations around sexual health and HIV prevention.

The One2PrEP campaign launched in January with high-profile placements during the Grammys and Super Bowl, and will continue through 2026 across TV, digital, social, print, dating apps, doctors’ offices, and community events.

Watch the Gilead One2Prep TV ad
Cultural Reach

Amgen

Amgen moderated a panel exploring the influence of professional athletes in shaping health conversations.

The discussion featured Pro Football Hall of Fame legend Barry Sanders, who survived a heart attack on Father’s Day 2024—making him a uniquely powerful advocate. If it can happen to him, it can happen to anyone, helping prevention feel relevant rather than remote.

Amgen previously collaborated with Sanders on its first documentary, The Making of a Heart Attack, which premiered in June 2025. Positioned as a long-term, education-led partnership rather than a one-off endorsement, the collaboration prioritizes trust, sustained advocacy, and credible awareness-building over time.

Explore Amgen’s Making of a Heart Attack
From the Floor

The SXSW Vibe

Authors

Our SXSW 2026 Austin team

Susie Spallina, Stephen Towers, Fred Liedtke, Luke Molloy
Want to explore further?

If you would like to learn more about any of the experiences at SXSW or explore how our teams can assist with planning an immersive experience, please reach out to:

MedComms@omnicomhealth.com